Is any one PA program better than any other? Well yes and no... They are all going to qualify you to sit for the certification exam and they're all held to the same standards by NAACLS. So in that sense they are all good programs and will allow you to be a pathologists' assistant (which, conceivably, is your goal, right?).
Each school has its advantages and disadvantages. The cost of tuition is not insignificant regardless of where you go, but if you're lucky you will be a resident in one of the states where being a resident can save you tens of thousands of dollars. However, tuition isn't the only cost since a big part of your loans will be allotted for living costs. The city you live in will make a big difference. The Durham area, for instance, is really quite affordable so for $600 you can get a two bedroom apartment and have a roommate.
Location matters, not just for cost of living, but for lifestyle reasons since Philadelphia is a very different city from Durham which is very different from Detroit, etc. Weather might also matter for some people, so if you don't like snow I would advise against going to school in Connecticut for instance. Plus, if you're close to your family and they live in Indiana then you probably wouldn't want to go to school here in North Carolina but would be thrilled with getting accepted into IUPUI.
There are differences in the programs to consider as well. How big do you want your class to be? Class sizes range from four to thirty three. How the classes are taught varies as well, we take all of ours with the Duke medical students which concentrates their didactic curriculum into a single year. In other schools you might have some classes with nursing students, some with dental students, some with physicians' assistants, while in the programs with larger enrollment numbers you might have PA only classes.
Rotations vary as well. We stay fairly localized for ours, while other programs send their students to other states, and even other regions of the country. That was actually a huge factor for me since I was bringing my kids along, I wanted them to be able to stay in the same school/state/environment for the two years I would be in graduate school and not have to worry about being sent to Texas or UCLA (of course if you're from a western state and would like to be closer to home, then one of those programs would be great!).
There are a lot of other factors. Each program is different and you can't look at one or the other and say in every instance, for ever case, there is one superior one. Apply to every program you think you could live with going to, because ultimate the best program--the absolute best one--is the one that accepts you as a student.